Last week I ran into a major problem with none of my saves being able to load because of a mannequin activation error. I noticed that skyui was also appearing in my installed and activated list in MO but that did not appear to affect anything. I was able to modify and configure mods with MCM without a problem.
This worked fine and everything ran normally. I got around that by installing it with NMM. To start I was not able to install it into MO for some reason. I am having an very weird problem with skyui and MO.